Lathyrogenic Activity in vitro
نویسندگان
چکیده
منابع مشابه
Structural Requirements for Lathyrogenic Agents
Using the chick embryo assay system, a series of organic compounds was tested for lathyrogenic activity; lathyrogenic compounds were shown to fall into 4 groups-nitriles, ureides, and 2 new groups-hydrazides and hydrazines, forming a spectrum of diminishing potency in their ability to produce solubility of collagen and skeletal deformities. Pyridoxal was seen to reverse to a great degree the ef...
متن کاملMetabolic Effects of Lathyrogenic Agents on Cartilage in Vivo and in Vitro
The effects of lathyrogenic agents in vivo and in vitro are described, in respect to some biochemical indices of cartilage metabolism. Lathyrogenic agents in vivo inhibited the incorporation of radiosulfate into rat epiphyseal cartilage and the isolated chondroitin sulfate. No significant changes in hydroxyproline or hexosamine content of epiphyseal cartilage were found, but there was a marked ...
متن کاملMetabolic Effects of Lathyrogenic Agents on Cartilage in Vivo and in Vitro* By
I t has been known for over twenty years that the feeding of sweet pea (Lathyrus odoratus) seeds to rats causes skeletal deformities (osteolathyrism) (1). Recently, Ponseti and co-workers (2) have revived interest in the experimental disease of osteolathyrism (or odoratism as it is sometimes called). The condition is characterised by severe and dramatic changes induced in the mesenchymal tissue...
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Background and objectives: Luteolin (3′,4′,5,7-tetrahydroxy flavone) is one of the most common flavones, which is naturally found in several edible plants and traditional medicine. It is known as a non-toxic compound with anti-inflammatory, antinociceptive, anticarcinogenic, antimutagenic, and antiangiogenic properties. Luteolin has antiproliferative activity against different ...
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Background and Objectives: The most common problems limiting the medical use of aminoglycosides have been the nephro- and oto-toxicities as well as the increasing bacterial resistance. Encapsulation of drugs into liposomes enhances their efficacy while reducing their toxicities. The aim of this study was to evaluate the antimicrobial activity of free and liposomal amikacin. Material and Metho...
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ژورنال
عنوان ژورنال: Nature
سال: 1961
ISSN: 0028-0836,1476-4687
DOI: 10.1038/192273a0